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Available online at Current Opinion in Pharmacology 2013, 13:829–833. chosen to focus on recent organs-on-a-chip that have ... engineering functional cardiac tissue on a flexible sub-strate cells using microfabrication technology. Heart muscle were cultured onto small tissue strips, where theyMyocardial tissue engineering for ... - ScienceDirect01-03-2016·The number of patients with heart failure is increasing in the aging population. Heart transplantation remains the only curative treatment option for …



Tissue Engineering - an overview | ScienceDirect Topics

Importantly, there have been many small-scale, yet successful, clinical applications of tissue engineering to human patients, including tissue-engineered trachea, bladder, blood vessel, and skin. Cardiac tissue engineering, in particular, involving the growth of cardiomyocytes into a complex and thick cardiac tissue, is a growing field, described in detail here.

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Native Blood Vessel - an overview | ScienceDirect Topics

Y. Hong, in Advances in Polyurethane Biomaterials, 2016 19.5.1 Blood vessel tissue engineering. Autologous vascular transplantation is the gold standard for treating coronary and peripheral vascular diseases. However, the resource for healthy autologous vasculatures is limited in terms of the age and health status of the patient.

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Cells for tissue engineering of cardiac valves

Heart valve tissue engineering is a promising alternative to prostheses for the replacement of diseased or damaged heart valves, because tissue-engineered valves have the ability to remodel, regenerate and grow. To engineer heart valves, cells are harvested, seeded onto or into a three-dimensional ( …

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Cardiac tissue engineering: current state-of-the-art ...

11-09-2018·Cardiovascular tissue engineering studies applying bioreactors involve blood vessels, heart valves (57 , 64 ) and cardiac tissue culture. (4 , 65 – 68 ) Cardiac tissue is extremely complex and bioreactors may help to better understand the influence of each parameter during the in vitro culture (Figure 4).

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Electrical coupling of cardiomyocyte sheets occurs rapidly ...

Previously, we have successfully created pulsatile myocardial tissue grafts using our novel technology, "cell sheet engineering", that layers cell sheets fabricated on temperature-responsive culture dishes to form three-dimensional (3-D) structures. Electrical coupling is established between layered …

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Cardiac Tissue Engineering - ScienceDirect

01-01-2014·The cardiac tissue engineering scaffolds are in general porous and perfusable to enable oxygen supply in vitro, , and designed to promote angiogenesis to enable oxygen supply in vivo, Some methods of cardiac tissue engineering do not utilize scaffolding material; for example, the cell sheet method , , , relies on stacking confluent sheets of cardiomyocytes and …

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Cardiac Tissue Engineering - an overview | ScienceDirect ...

32 行·Cardiac tissue engineering (CTE) aims to create contractile tissues to replace damaged or missing myocardial tissues. Biomaterials/scaffolds constitute a major component in various strategies of CTE, as stand-alone treatments …

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Conductive polypyrrole-encapsulated ... - sciencedirect

01-09-2021·1. Introduction. Cardiac tissue engineering (CTE) is a promising solution for myocardial infarction that has a high recurrence rate, morbidity, and mortality [].One of the main strategies in CTE is the scaffold-based approach, also known as the engineered cardiac patch.

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Harnessing nanotechnology for cardiovascular disease ...

In tissue engineering, cardiac tissue, in contrast to other tissues, is an extremely complicated structure. There are insufficient tools to measure and rebuild it in sufficient detail [214] . The nano-scaffold-based cardiac patch shows great clinical transfer potential, but the need for invasive surgery to implant the patch ultimately limits its application [215] .

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Engineered cardiac tissues - PubMed

Cardiac tissue engineering offers the promise of creating functional tissue replacements for use in the failing heart or for in vitro drug screening. The last decade has seen a great deal of progress in this field with new advances in interdisciplinary areas such as developmental biology, genetic engineering, biomaterials, polymer science, bioreactor engineering, and stem cell …

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Tissue Engineering - an overview | ScienceDirect Topics

Importantly, there have been many small-scale, yet successful, clinical applications of tissue engineering to human patients, including tissue-engineered trachea, bladder, blood vessel, and skin. Cardiac tissue engineering, in particular, involving the growth of cardiomyocytes into a complex and thick cardiac tissue, is a growing field, described in detail here.

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Cardiac tissue engineering - PubMed

Cardiac tissue engineering Transpl Immunol. 2002 May;9(2-4):315-21. doi: 10.1016/s0966-3274(02)00011-4. Authors Thomas Eschenhagen 1 , Michael …

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Cardiac tissue engineering - ScienceDirect

01-02-2013·the goal of cardiac tissue engineering is to repair, regenerate or replace damaged native tissues through, first, cell transplantation, second, in vitro engineering of cardiac tissues to be implanted for cardiac repair, and third, design of bioactive biomaterials to be used for in situ cardiac repair through promoting vascularization or cell …

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Conductive nanomaterials for cardiac tissues engineering

one of the important components of cardiac tissue engineering, bioma- terials play an extremely important role in the construction of ECTs in vitro and repair of damaged myocardium in vivo , …

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Cardiac Tissue Engineering - Summarized by Plex.page ...

Cardiac Tissue Engineering. Collected from the entire web and summarized to include only the most important parts of it. Can be used as content for research and analysis.

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Harnessing nanotechnology for cardiovascular disease ...

In tissue engineering, cardiac tissue, in contrast to other tissues, is an extremely complicated structure. There are insufficient tools to measure and rebuild it in sufficient detail [214] . The nano-scaffold-based cardiac patch shows great clinical transfer potential, but the need for invasive surgery to implant the patch ultimately limits its application [215] .

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SARS-CoV-2 Infects Human Engineered Heart Tissues and ...

04-11-2020·After infection with SARS-CoV-2, engineered tissues display typical features of myocarditis, including cardiomyocyte cell death, impaired cardiac contractility, and innate immune cell activation. Consistent with these findings, autopsy tissue obtained from individuals with COVID-19 myocarditis demonstrated cardiomyocyte infection, cell death, and macrophage …

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Cells for tissue engineering of cardiac valves

Heart valve tissue engineering is a promising alternative to prostheses for the replacement of diseased or damaged heart valves, because tissue-engineered valves have the ability to remodel, regenerate and grow. To engineer heart valves, cells are harvested, seeded onto or into a three-dimensional ( …

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Tissue Regeneration - an overview | ScienceDirect Topics

Tissue regeneration is an emerging field that endeavors to prolong people's life expectancy by replacing damaged organs with architected organs, including the kidneys. The kidney is one of the body's most important organs because of the vital role it plays in purifying the body.

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Tissue Engineering - an overview | ScienceDirect Topics

Tissue Engineering. Tissue engineering (TE) is a rapidly evolving discipline that seeks to repair, replace or regenerate tissues or organs by translating fundamental knowledge in physics, chemistry and biology into practical and effective materials, or devices and clinical strategies.37,38. From: Tissue Engineering Using Ceramics and Polymers, 2007

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Conductive nanomaterials for cardiac tissues engineering

one of the important components of cardiac tissue engineering, bioma- terials play an extremely important role in the construction of ECTs in vitro and repair of damaged myocardium in vivo , …

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中国团队「六轴细胞3D打印机」登生物材料顶刊!心肌组织可体外 …

03-03-2022·新智元报道 编辑:好困【新智元导读】最近,由中国科学院遗传与发育生物学研究所的王秀杰研究员、曼彻斯特大学的王昌凌教授和清华大学的刘永进教授带领的团队,提出了一种新型3D生物打印体系,并登上了生物材料领域顶级期刊。生物3D打印(3D Bioprinting)技术利用3D打印机将含有细胞和生物 ...

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[Cardiac tissue engineering] - PubMed

Background: Cardiac tissue engineering is a relatively new interdisciplinary approach to replace diseased cardiovascular tissues with vital structures based on autologous cells. Various forms: This includes the re-seeding of decellularized allogenic or xenogenic scaffolds with autologous cells, the fabrication of organoids based on artificial, biodegradable polymers, and cell …

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Electrical coupling of cardiomyocyte sheets occurs rapidly ...

Previously, we have successfully created pulsatile myocardial tissue grafts using our novel technology, "cell sheet engineering", that layers cell sheets fabricated on temperature-responsive culture dishes to form three-dimensional (3-D) structures. Electrical coupling is established between layered …

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